Optical Radiology Labs at Washington University in St. Louis School of Medicine

Publications from 2012


  1.  S.W. Tsen, T. Chapa, W. Beatty, K.T. Tsen, D. Yu, S. Achilefu: Inactivation of enveloped virus by laser-driven protein aggregation. J. Biomed Opt 17 128001-8 (2012)

  2. J. Xue, L. Shan, H. Chen, Y. Li, H. Zhu, D. Deng, Z. Qian, S. Achilefu, Y. Gu: Visual detection of STAT5B gene expression in living cell using the hairpin DNA modified gold nanoparticle beacon.  Biosens Bioelectron doi: 10.1016/j.bios (2012)

  3. Y. Liu, T. York, W. Akers, G. Sudlow, V. Gruev, S. Achilefu: Complementary fluorescence-polarization microscopy using division-of-focal-plane polarization imaging sensor. J Biomed Opt doe: 10.1117/1 (2012)

  4. H. Lee, M.Y. Berezin, R. Tang, N. Zhegalova, S. Achilefu: Pyrazole-substituted near-infrared cyanine dyes exhibit pH-dependent fluorescence lifetime properties. Photochem Photobiol doe: 10.1111/php.12009 (2012)

  5. J. C. Gildersleeve, B. Wang, S. Achilefu, Z. Tu, M. Xu: Glycan array analysis of the antigen repertoire targeted by tumor-binding antibodies. Bioorg Med Chem Lett 22 6839-6843 (2012)

  6. H. Chen, S. Li, B. Li, X. Ren, S. Li, D.M. Mahounga, S. Cui, Y. Gu, S. Achilefu:  Folate-modified gold nanoclusters as near-infrared fluorescent probes for tumor imaging and therapy. Nanoscale 4 6050-6064 (2012)

  7.  Y. Ye, W. J. Akers, B. Xu, S. Bloch, C. Odonkor, S. Achilefu: Near-infrared fluorescent divalent RGD ligand for integrin avb3-targeted optical imaging.  Bioorg Med Chem .Lett 22 5405-5409 (2012) 

  8. R. Nothdurft, P. Sarder, S. Bloch, J. Culver,  S. Achilefu: Fluorescence lifetime imaging microscopy using near-infrared contrast agents. J. Microsc. 247 202-7 (2012) 

  9. X. Zhang, S. Bloch, W. Akers, S. Achilefu: Near-infrared molecular probes for in vivo imaging. Curr Protoc Cytom 12.27.1-20 (2012) PMCID: PMC3334312 

  10. V. Korotcov, Y. Yunpeng, Y. Chen, F. Zhang, S. Huang, S. Lin, R. Sridhar,S. Achilefu, P.C. Wang: Glucosamine-linked near infrared fluorescent probes for imaging of solid tumor xenografts. Mol Imag Biol 14 443-451 (2012)

  11. J. Guo, C. Du, L. Shan, H. Zhu, B. Xue, Z. Qian, S. Achilefu, Y. Gu: Comparison of near-infrared fluorescent deoxyglucose probes with different dyes for tumor diagnosis in vivo. Contrast Media Mol Imaging 7 289-301 (2012) 

  12. H. Li, Z. Tu, L. An, Z. Qian, S. Achilefu, Y. Gu: Inhibitory effects of Erbeta on proliferation, invasion, and tumor formation of MCF-7 breast cancer cells-prognostication for the use of ER ? –selective therapy. Pharm Biol 50 839-49 (2012)

  13. Z. Tu, H. Li, Y. Ma, B. Tang, J. Tian, W. Akers, S. Achilefu, Y. Gu: The enhanced antiproliferative response to combined treatment of trichostatin A with raloxifene in MCF-7 breast cancer cells and its relevance to estrogen receptor ? expression. Mol Cell Biochem 366 111-122 (2012) 

  14. B. Xue, D. Deng, J. Cao, F. Liu, X. Li, W. Akers, S. Achilefu, Y. Gu: Synthesis of NAC capped near infrared-emitting CdTeS alloyed quantum dots and application for in vivo early tumor imaging. Dalton Trans., 41 4935-4947 (2012) 

  15. Tu, Z. Y. Ma, J. Tian, H. Li, W. Akers, S. Achilefu, Y. Gu: Estrogen receptor ? potentiates the antiproliferative effect of raloxifene and affects the cell migration and invasion in HCT-116 colon cancer cells. J Cancer Res Clin Oncol 138 1091-1103 (2012) 

  16. S. Achilefu: Rapid response activatable molecular probes for intraoperative optical image guided tumor resection. Hepatology (2012) doi: 10.1002/hep.25807 

  17. Y. Ardeshirpour, V. Chernomordik, R. Zielinski, J. Capala, G. Griffiths, O. Vasalatiy, A.V. Smirnov, J.R. Knutson, I. Lyakhov, S. Achilefu, A. Gandjbakhche, M. Hassan: In vivo fluorescence lifetime imaging monitors binding of specific probes to cancer biomarkers. PLoS One 7 1-14 (2012) 

  18. R. Tang, H. Lee, S. Achilefu: Induction of pH sensitivity on the fluorescence lifetime of quantum dots by NIR fluorescent dyes. J. AM. Chem. Soc. 134 4545-4548 (2012) PMCID: PMC3303939 

  19. W.J. Akers, W.B.Edwards, C. Kim, B. Xu, T.N. Erpelding, L.V. Wang, S. Achilefu: Multimodal sentinel lymph node mapping with single-photon emission computed tomography (SPECT)/computed tomography (CT) and photoacoustic tomography. Transl Res 159 175-181 (2012) PMCID: PMC3286037 

  20. Wang, J. Moore, S. Laulhe, M. Nantz, S. Achilefu, K.A. Kang: Fluorophore-gold nanoparticle complex for sensitive optical biosensing and imaging. Nanotechnology 23 1-13 (2012) 

  21. W.J. Akers, B. Xu, H. Lee, G. Sudlow, G.B. Fields, S. Achilefu, W.B. Edwards: Detection of MMP-2 and MMP-9 activity in vivo with a triple-helical peptide optical probe. Bioconjug Chem 3 656-663 (2012) PMCID: PMC3310325 

  22. T.P. Gustafson, Q. Cao, S. Achilefu, M.Y. Berezin: Defining a polymethine dye for fluorescence anisotropy applications in the near-infrared spectral range. Chemphyschem 13 716-23 (2012) 

  23. J.M. Craft, R.A. De Silva, K.A. Lears, R. Andrews, K. Liang, S. Achilefu, B.E. Rogers: In vitro and in vivo evaluation of a (64)Cu-labeled NOTA-Bn-SCN-Aoc-bombesin analogue in gastrin-releasing peptide receptor expressing prostate cancer. Nucl Med Biol. 39 609-616 (2012) PMCID: PMC3341490 

  24. K.A. Kang, J. Wang, M.G. O’Toole, M. Nantz, J.D. Moore, S. Laulhe, S. Achilefu: Sensitivity enhancement of NIR fluorescence contrast agent utilizing gold nanoparticles. Adv Exp Med Biol. 737 285-91 (2012) 

  25. K. Guo, S. Achilefu, M.Y. Berezin: Dating bloodstains with fluorescence lifetime measurements. Chem. Eur. J. 18 1302-1305 (2012) 

  26. Xu, M. Rettig, G. Sudlow, B. Wang, W. Akers, D. Cao, D. Mutch, J. Dipersio, S. Achilefu: Preclinical evaluation of mab CC188 for ovarian cancer imaging. Int J Cancer DOI: 10.1002/ijc.27380 (2012) 

  27. L. Shan, S. Cui, C. Du, S. Wan, Z. Qian, S. Achilefu, Y. Gu: A paclitaxel-conjugated adenovirus vector for targeted drug delivery for tumor therapy. Biomaterials 33 146-162 (2012) 

  28. M.B. Aldrich, M.V. Marshall, E.M. Sevick-Muraca, G. Lanza, J. Kotyk, J. Culver, L.V. Wang, J. Uddin, B.C. Crews, L.J. Marnett, J.C. Liao, C. Contag, J.M. Crawford, ?K. Wang, B. Reisdorph, H. Appelman, D.K. Turgeon, C. Meyer, and T. Wang: Seeing it through: translational validation of new medical imaging modalities. Biomed Optics Express 3(4) 64-76 (2012) PMCID: PMC3345805

  29. A.W. Bero, A.Q. Bauer, F. R. Stewart, B.R. White, J.R. Cirrito, M.E. Raichle, J.P. Culver, and D.M. Holtzman: Bidirectional relationship between functional connectivity and amyloid-β deposition in mouse brain. J Neurosci. 32(13) 4334–4340 (2012) PMCID: PMC3326343

  30. S.M. Liao, S.L. Ferradal, B.R. White, N. Gregg, T.E. Inder, and J. P. Culver: High-density diffuse optical tomography of term infant visual cortex in the nursery. J Biomed Opt. 17(8): 81414 (2012) PMCID: PMC3391961

  31. R. Nothdurft, P. Sarder, S. Bloch, J. Culver,?  and S. Achilefu: Fluorescence lifetime imaging microscopy using near-infrared contrast agents. Journal of Microscopy, 247(2) 202–207 (2012) PMID: 22788550

  32. Y. Zhan, A.T. Eggebrecht, J.P. Culver, and H. Dehghani: Singular value decomposition based regularization prior to spectral mixing improves crosstalk in dynamic imaging using spectral diffuse optical tomography. Biomed Opt Express. 3(9) 2036-49 (2012) PMCID: PMC3447547

  33. Y. Zhan, A.T. Eggebrecht, J.P. Culver, and H. Dehghani: Image quality analysis of high-density diffuse optical tomography incorporating a subject-specific head model. Front Neuroenergetics 4: 6 (2012) PMCID: PMC3359425

  34. Gustafson TP, Yan Y, Newton P, Hunter DA, Achilefu S, Akers WJ, Mackinnon SE, Johnson PJ, Berezin MY, 'A Nir Dye for Development of Peripheral Nerve Targeted Probes', Medchemcomm 2012, 3, 685-90.PMCID: PMC3932509.



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©2011 Mallinckrodt Institute of Radiology     Last Modified on April 13th