Optical Radiology Labs at Washington University in St. Louis School of Medicine
Julie L. Prior

Julie L. Prior

Research Lab Supervisor
Washington University School of Medicine
Department of Radiology
Campus Box 8225
4515 McKinley Ave Room 2309



  • St. Mary’s University of MN, 1995
    BA in Biology


Research Interests

Small animal imaging, including bioluminescence, fluorescence, SPECT and PET, as a means to study molecular events in the context of cancer and other diseases, as well as for the evaluation of new therapeutics and imaging agents.


Publications (Selected)

  • Zhang K, Corsa CA, Ponik SM, Prior JL, Piwnica-Worms D, Eliceiri KW, Keely PJ, Longmore GD.  The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis.  Nat Cell Biol 2013, 15:677-87. 
  • Chinault SL, Prior JL, Kaltenbronn KM, Penly A, Weilbaecher KN, Piwnica-Worms D, Blumer KJ.  Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter.  Clin Cancer Res 2012, 18:4136-44.
  • Pazolli E, Alspach E, Milczarek A, Prior J, Piwnica-Worms D, Stewart SA.  Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression.  Cancer Res 2012, 72:2251-61.
  • Choi J, Ritchey J, Prior JL, Holt M, Shannon WD, Deych E, Piwnica-Worms DR, DiPersio JF.  In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.  Blood, 2010, 116:129-39.
  • Pichler A, Prior JL, Luker GD, Piwnica-Worms D.  Generation of a highly inducible Gal4-->Fluc universal reporter mouse for in vivo bioluminescence imaging.  Proc Natl Acad Sci U S A 2008, 105:15932-7.
  • Harpstrite SE, Prior JL, Rath NP, Sharma V.  Metalloprobes: synthesis, characterization, and potency of a novel gallium(III) complex in human epidermal carcinoma cells.  J Inorg Biochem 2007, 101:1347-53.



Hiking, traveling, reading.

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