Optical Radiology Labs at Washington University in St. Louis School of Medicine
Julie L. Prior

Julie L. Prior

Research Lab Supervisor
314-362-9357
priorj@mir.wustl.edu
Washington University School of Medicine
Department of Radiology
Campus Box 8225
4515 McKinley Ave Room 2309

 

Education

  • St. Mary’s University of MN, 1995
    BA in Biology

 

Research Interests

Small animal imaging, including bioluminescence, fluorescence, SPECT and PET, as a means to study molecular events in the context of cancer and other diseases, as well as for the evaluation of new therapeutics and imaging agents.

 

Publications (Selected)

  • Zhang K, Corsa CA, Ponik SM, Prior JL, Piwnica-Worms D, Eliceiri KW, Keely PJ, Longmore GD.  The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis.  Nat Cell Biol 2013, 15:677-87. 
  • Chinault SL, Prior JL, Kaltenbronn KM, Penly A, Weilbaecher KN, Piwnica-Worms D, Blumer KJ.  Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter.  Clin Cancer Res 2012, 18:4136-44.
  • Pazolli E, Alspach E, Milczarek A, Prior J, Piwnica-Worms D, Stewart SA.  Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression.  Cancer Res 2012, 72:2251-61.
  • Choi J, Ritchey J, Prior JL, Holt M, Shannon WD, Deych E, Piwnica-Worms DR, DiPersio JF.  In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.  Blood, 2010, 116:129-39.
  • Pichler A, Prior JL, Luker GD, Piwnica-Worms D.  Generation of a highly inducible Gal4-->Fluc universal reporter mouse for in vivo bioluminescence imaging.  Proc Natl Acad Sci U S A 2008, 105:15932-7.
  • Harpstrite SE, Prior JL, Rath NP, Sharma V.  Metalloprobes: synthesis, characterization, and potency of a novel gallium(III) complex in human epidermal carcinoma cells.  J Inorg Biochem 2007, 101:1347-53.

 

Hobbies

Hiking, traveling, reading.

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©2011 Mallinckrodt Institute of Radiology     Last Modified on April 21st