Optical Radiology Labs at Washington University in St. Louis School of Medicine

Innovative light therapy reaches deep tumors
Using a mouse model of cancer, the Achilefu Lab have devised a way to apply light-based therapy to deep tissues never before accessible. Instead of shining an outside light, they delivered light directly to tumor cells, along with a photosensitive source of free radicals that can be activated by the light to destroy cancer. And they accomplished this using materials already approved for use in cancer patients. The study appears March 9 in the journal Nature Nanotechnology. Congratulations to the authors - Samuel Achilefu, Nalinikanth Kotagiri, Gail Sudlow and Walter Akers!
Read more: Innovative light therapy with nanophotosensitizers reaches deep tumors

 

titanium dioxide nanoparticle

The titanium dioxide nanoparticle is shown here (purple)

carrying the iron-binding protein transferrin (blue and green)

and the light-sensitive cancer drug titanocene (red).

 




 

The fluorescence goggle system developed by ORL was used for image guided biopsy of the sentinel lymph node in a breast cancer patient.

  

 



 

Dr. Achilefu receives prestigious St. Louis Award ​​​for cancer goggles

Washington University Chancellor Emeritus William H. Danforth (left) visits with Samuel Achilefu, PhD, after Achilefu received the St. Louis Award on Wednesday, Jan. 14, on the Medical Campus. The honor recognizes area residents whose achievements reflect positively on the community. Danforth received the honor in 2012.

 

 

 

 

 

 

 

ORL Updates:
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Michel M. Ter-Pogossian Professorship Installation


Novel nanoparticle made of common mineral may help keep tumor growth at bay



©2011 Mallinckrodt Institute of Radiology     Last Modified on March 8th