Dr. Akers is currently investigating optical imaging techniques for detecting molecular signatures of cancer and cardiovascular disease using fluorescent contrast agents. Novel fluorescent molecular probes are assayed for sensitivity and specificity in preclinical animal models using fluorescence intensity and fluorescence lifetime imaging systems. Preclinical studies are focused on imaging of cancer-related enzyme activity using activatable fluorescent probes in breast cancer models. The overarching aim of Dr. Akers’ research is translation of optical imaging methods to clinical applications in human medicine. Translational projects include multimodal sentinel lymph node mapping for breast cancer staging and fluorescence guided surgery as part of glioblastoma treatment.
For an up to date list of Dr. Akers's publications please see his entry on PubMed.